Qwo is the first FDA-Approved Injectable Cellulite Treatment that releases deep dimples by dissolving the fibrous bands that cause them, with a simple injection of a safe drug that’s been used for years in other medical applications.
Cellulite is a complex multi-factorial condition hallmarked by fat trapped in the dermal layer of your skin leading to dimpling, waviness, “orange peel” or “cottage cheese” appearing skin texture and/or overall less smooth contour irregularity. The dimpling is often caused by “fibrous septae.”
QWO injected by Dr. Nusbaum works by enzymatically disrupting the fibrous septae responsible for creating cellulite resulting in a smoother appearance of the treated skin.
Enzymatic Subcision and Remodeling (ESR™) describe the mechanism of action of Qwo™injections. Qwo™is an injectable formulation that consists of two enzymes that degrade collagen molecules. When Qwo™ is injected into the area beneath a dimple, it stimulates the initiation of ESR. ESR involves the enzymatic degradation of collagen-rich fibrous septae which play a key role in the pathophysiology of cellulite. Disrupting these subdermal fibrous structures, Qwo™causes the release of cellulite-associated skin depressions and smooths the surface of the skin. Furthermore, Qwo™stimulates the production of new collagen molecules (neocollagenesis) which further improves the appearance of the skin.
QWO injections with Dr. Nusbaum have been FDA-approved to treat dimples aka cellulite on the buttocks. However, Dr. Nusbaum routinely has patients voicing concerns about contour irregularity and cellulite on the back of their thighs. This is an off-label treatment area that can be done as well.
Qwo is primarily comprised of CCH-Collagenase Clostridium histolyticum. Collagenase Clostridium histolyticum aka CCH aka QWO with Dr. Nusbaum is an enzyme that breaks down collagen (specifically Type 1 and Type 3) in specific tissues to help the body create new and better-quality skin.
QWO has been studied in several hundred patients who have undergone a cumulative of over a thousand treatments. The treatment seems to be very safe with adverse events like other cosmetic injectable treatments, such as bruising.
QWO is a clear, odorless water-like mixture that is injected through tiny needles into the dimples responsible for creating the appearance of cellulite.
To-date, we have data to support longevity for a few years and will continue to monitor how many years patients can expect to see the substantial improvement.
Patients who have undergone QWO injections with Dr. Nusbaum typically have bruising that can last one to two weeks after the first treatment. Patients report mild to moderate soreness alleviated with Tylenol or ibuprofen. There is mild to moderate swelling for the first few days, as well. Dr. Nusbaum permits his patients to go to the gym and lead an active lifestyle the day after being treated with QWO. So as you can see, there really isn’t any “downtime.”
Patients may see an improvement as early as three weeks after their injections. However, the improvement continues, and most patients require more than one treatment cycle of QWO. Up to a maximum of three treatments are needed spaced 3 weeks (21 days) apart.